Murray got the best of a much-anticipated showdown with Cleveland quarterback Baker Mayfield. The two were teammates in college at Oklahoma and both won Heisman Trophies before being selected with the No. 1 overall picks by their respective teams in back-to-back years.
Murray completed 19 of 25 passes and also ran for 58 yards. Drake, acquired mid-season in a trade with the Dolphins, ran for a season-high 137 yards and scored a touchdown in every quarter. He’s the first Cardinals player to score four rushing touchdowns in a game since 1993.
Cleveland’s Nick Chubb — who came in as the NFL’s leading rusher — finished with 127 yards on the ground. Mayfield completed 30 of 43 passes for 247 yards, two touchdowns and one interception.
The Cardinals had 299 total yards in the first half, including 145 on the ground. They finished with 445 yards and got just their 4th win of the season.
Browns are home next Sunday with Baltimore.