Clemson Tigers quarterback Trevor Lawrence has tested positive for COVID-19 and will miss Saturday’s game against Boston College.

“Trevor has authorized us this evening to announce that he has tested positive for COVID-19 and is now in isolation,” Clemson coach Dabo Swinney said in a statement Thursday night. “He is doing well with mild symptoms but will not be available for this week’s game against Boston College.

Lawrence is a front-runner for the Heisman Trophy, and he has not missed a game in three seasons at Clemson.

Lawrence’s COVID-19 test was taken Wednesday. Under the rules established by the ACC’s medical advisory group, any player who tests positive for COVID-19 must isolate for at least 10 days after the test before returning to practice, assuming they no longer are showing symptoms. That would also put Lawrence at risk of missing the top-ranked Tigers’ Nov. 7 showdown at No. 4 Notre Dame.