The Arizona Cardinals have more clarity on their quarterback situation less than two weeks before Week 1.

Kyler Murray won’t be activated off the physically unable to perform list before Tuesday’s 4 p.m. ET deadline, Cardinals coach Jonathan Gannon said Monday.

Starting the season on the PUP list means Murray will miss at least the first four games of the regular season. Once he’s activated, he’ll have 21 days to practice and be put on the 53-man roster, otherwise he’ll have to spend the entire season on the PUP list.

The Cardinals also released quarterback Colt McCoy on Monday, a day before teams are required to narrow their roster to 53 players. The move comes four days after they traded for quarterback Joshua Dobbs. McCoy, the 36-year-old who signed with the Cardinals in 2021, was the first-team quarterback all spring, training camp and preseason while Arizona waited for Murray to return from ACL surgery.

Gannon said the Cardinals evaluated McCoy’s “full body of work” and decided it was in the best interest of Arizona to start the season without him.

“I don’t think it’s anything he didn’t show us,” Gannon said. “I think it was just looking at OTAs and then training camp and the games and the full body of work, we just feel like this is the best way to go.”

Murray injured his right knee in Week 14 last season on “Monday Night Football” and had surgery in early January. Murray had said previously that he wanted to be back by Week 1. He later said he didn’t want to miss any time but he also isn’t sure how much practice he’ll need before he’s ready to take a regular-season snap.

Should Murray miss at least the first four games, Gannon said the quarterback’s rehab approach won’t be altered.

“He’s got a plan that’s football related, and he’s got a plan that’s rehab related, and both are important, but obviously the plan that’s most important right now is his health,” Gannon said. “So, when we structure his day and his week and this last month with him, we plan accordingly for that.”

With McCoy’s release and Murray not being available for Week 1 against the Washington Commanders, the Cardinals will likely choose their starter from Dobbs and fifth-round pick Clayton Tune.