Lamar Jackson threw for a franchise-record 442 yards and four touchdowns, leading the biggest comeback of his career in an epic 31-25 overtime victory over the Indianapolis Colts on Monday night. His five-yard touchdown pass to Brown in overtime lifted Baltimore (4-1) to its fourth straight win and into sole possession of first place in the AFC North.

Jackson endured one of the worst starts of his career, managing the fewest first-half points (three) in his 42 starts. His fumble at the Colts’ 2-yard line led to Baltimore trailing 22-3 with 3:06 left in the third quarter, which seemed liked an insurmountable deficit considering the Ravens were 0-17 when trailing by 19 or more points in Harbaugh’s 14 seasons.

Jackson accounted for 499 of the Ravens’ 523 yards for an offense that lost wide receiver Sammy Watkins (hamstring) and guard Ben Cleveland (knee) to injuries in the first half.

The Ravens had to withstand a 47-yard field goal attempt by Rodrigo Blankenship on the final play of regulation, but the Indianapolis kicker missed, sending the teams to overtime.

The Ravens had their record-tying streak of 43 straight 100-yard rushing games snapped, and it looked like they were in big trouble after Jackson fumbled near the goal line in the third quarter. But after that turnover, Baltimore scored a touchdown on each of its final four possessions.

The Indianapolis kicking game was a big reason the game got to overtime. Blankenship — who hurt a hip in warmups — missed an extra point in the third quarter. With the Colts up 25-17, he had a 37-yard kick blocked by Calais Campbell with 4:29 remaining, giving the Ravens a chance to tie the game.